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Dynorphin, stress, and depression - An analysis of the kappa opioid receptor system, chronic stress, and their influence on behavior and emotion

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Dynorphin, stress, and depression - An analysis of the kappa opioid receptor system, chronic stress, and their influence on behavior and emotion

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Noötropics refrence Carl Sagan's old book, "Contact", from 1985

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Noötropics refrence Carl Sagan's old book, "Contact", from 1985

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The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age (April 2019) "... results provide further evidence that early exposure to antibiotics may be associated with detrimental neurodevelopmental outcomes."

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Direct evidence for the involvement of intestinal reactive oxygen species in the progress of depression via the gut-brain axis

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The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Cognitive function improvement with astaxanthin and tocotrienol intake: a randomized, double-blind, placebo-controlled study

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

"The dopamine system of healthy, highly creative people is similar to that found in people with schizophrenia" - Science Codex

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

"The dopamine system of healthy, highly creative people is similar to that found in people with schizophrenia" - Science Codex

Post image
The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Changes in brain striatum dopamine and acetylcholine receptors induced by chronic CDP-choline treatment of aging mice. - PubMed

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Exploring Problematic TikTok Use and Mental Health Issues: A Systematic Review of Empirical Studies - PubMed 2025

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Exploring Problematic TikTok Use and Mental Health Issues: A Systematic Review of Empirical Studies - PubMed 2025

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

The Drug War and User Culture - An exploration of the social psychology

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Altered cerebral GABA-A receptor binding in post-traumatic stress disorder. -PubMed

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Convince me Benadryl is bad as a sleep aid when used 3+ times a week

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Convince me Benadryl is bad as a sleep aid when used 3+ times a week

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Sub-chronic exposure to atomoxetine up-regulates BDNF expression and signalling in the brain of adolescent spontaneously hypertensive rats: comparison with methylphenidate. (Though neither of these are considered nootropics, they're VERY popular in this community, worth a read!)

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Study: Effect of Exercise Intensity on Nrf2 Signaling in Young Men [Exercise as a nootropic, Nrf2 is the same pathway induced/activated by the nootropic Sulforaphane]

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Making Sense of Madness: Stress-Induced Hallucinogenesis - neuroscience

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Regular exercise appears to enhance and even grow crucial areas of the human brain important for memory and learning, new research using MRI scan on 10,125 individuals shows

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Drinking water can make you more productive: Even mild dehydration can impair cognition

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Drinking water can make you more productive: Even mild dehydration can impair cognition

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Study found that when people blocked mobile internet on their smartphones for just two weeks, they experienced better mental well-being, felt happier, and showed improved attention spans.

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.