The future of 4 subbed tryptamine psychedelics

Any info what is the predicted future of 4-subbed tryptamines like 4-AcO-DMT, 4-HO-MET, 4-HO-DET and so on? As far as I know most of them are still legal in the Netherlands and a lot of other countries but they are becoming harder to get and the variety is getting smaller. 4-HO-DET is already gone in the EU. 4-HO-DiPT gone for a long time now. I didnt have any chance to try it. Impossible to get in the EU. Seen in Canada

I am worried that eventually they will all be gone. They are not too popular and hard to synthetize.