Could CFS be a brain injury?

I was watching a documentary about CTE in the NFL. The one former player was being interviewed and it just reminded me of bad brain fog. The mental fatigue and the struggle to find words. The confusion and just being spaced out. I was researching further and I read bad fatigue was common in brain injuries. I am wondering if the pathology of CFS could be sometype of brain injury triggered by a virus or illness?