What medications have you guys had experience with?

I was prescribed Zoloft in the recent past and now my primary doctor has been wanting me to take mirtazapine, for my mood and my sleep. I'm very hesitant with drugs because I simply don't believe in them working on me or too scared of getting bad side effects. Are medications like SSRI's and so on even helpful for schizoids? What is kind of the point of having more serotonin? What medications would you suggest instead maybe I can ask them about?