First 6 Weeks, Wondering/Feedback

Hello TRT community,

I started TRT around 6 weeks ago and feeling much better than before. Increased libido, increased energy, and all around positives. I just had my 6 week labs and to discuss the next steps with my provider. The provider raised some concerns about my E2 levels. To get a second opinion wanted to see what the community thought?

Physical:

  • Weight: 400lbs
  • Height: 6'1
  • Activity:
    • One of my reasons going back on Trt is to fix my constant fatigue, which it has.
    • I've been as low as 290lbs and that is my goal with Trt is to get back there

Current Dosage:

  • Test Cypio 200mg/mL, 0.5mL, muscle once weekly
    • injecting into thigh 25ga needle
  • Clomid 55mg(haven't taken yet as one to change one thing at a time)

Initial Labs(6 weeks ago):

  • Test Total: 287 ng/dL
    • Historical was 589 in 2020
  • LH 3.2 mIU/mL
  • E2: Unknown
    • Historical last time it was checked in 2020 was 39
  • Hemoglobin: 15.6 g/dL
  • Hemocrit: 46.4%

New labs(as of last week):

  • Test Total: 736 ng/dL
  • LH: 0.2 mlU/mL
  • E2: 85 pg/mL
  • Hemoglobin: 16.5 g/dL
  • Hemocrit: 49.1%

Changes for next treatment:

  • Test Cypio 200mg/Ml, 0.5Ml muscle once weekly
  • Clomid 55mg(might start taking...)
  • Anastrozole 0.5mg
  1. Seen numerous posts about clomid and wondering is it worth taking?
  2. Same for Ana?
  3. Is 85 estrogen high for my weight?
  4. Would it help to change my dosage amounts and increase frequency to help with E2?

Thank you