My haematologist experience - Reproductive immunology testing

I recently posted this and thought I'd follow up for anyone curious: https://old.reddit.com/r/recurrentmiscarriage/comments/1fd5qsb/been_referred_to_a_haematologist_what_to_expect/

Turns out this particular haematologist specialises in a number of things and so I'll share my results (as best as I can understand them - I'm still learning).

Initially I was tested for cardiolipin and lupus anticoagulant, Protein C, Protein S, Activated Protein C Resistance, Factor V Leiden Mutation, Prothrombin Mutation, Homocysteine, Antithrombin III, B2 Glycoprotein, MTFHR gene, ANA.

  • ANA came back 1:320 speckled pattern. Followed up with ENA test but this came back fine. Was told 'some autoimmune activity' based on the ANA result but nothing that points to a diagnosis. I did have this tested about 2 weeks after a MC so not sure if that contributes.
  • No blood clotting disorders.
  • Was tested further for antiphospholipid syndrome and NK cells and these were fine.
  • Tested further for the genes related to celiac and I have the HLA-DQ8 and HLA-DQ2.2 genes.
  • MTFHR came back heterozygous and was told I need to keep my b12 up.

Essentially, no diagnosis was made however, the protocol I'll be on moving forward is a strict gluten-free diet and Plaquenil (I'll start this 5-6 weeks before next embryo transfer or start during pregnancy if I achieve a spontaneous pregnancy).

The one result that stands out is the celiac result. I have a number of family members with celiac disease (3 first cousins, 1 aunty, brother breaks out in rashes from wheat but no diagnosis) and I have many of the symptoms of celiac disease. I always just put it down to IBS and extreme fatigue caused by endo. I've only been GF for two days so it's too early to tell if is working but I'd like to eventually seek a formal diagnosis.

I am still yet to have an endometrial biopsy (17 Oct).

For some further medical context I have stage 4 endometriosis, adenomyosis, lichen sclerosis, eczema, and raynaud's. I am also in Australia so I'm not sure how much this approach differs from other countries.

Hope this helps anyone who stumbles upon it. Feel free to share your own results here, I'd be curious. Especially if you had a celiac diagnosis.