electrical hum from guitar recordings.

Hey yall, need some help on something. Ive pretty much tried everything to decrease the electrical buzz coming from my clean guitar recordings. Lowering my gain completely on my 2i4 and using the input gain on my neural plugins, shutting off all electronics around me to decrease static noise, even using rx11 spectral de-noiser which very little luck. Ive heard a DI box is a good option to help this cause. Any input from some experienced guitar trackers? thanks!