Characters that are transparently stand ins for real people
A man only credited as "The Art Teacher" from the Boondocks- Bob Ross
The Mayor from the Amazing World of Gumball- Trump
Jack Chiles from Seinfeld- Johnnie Cochran
Johnny Fontaine from The Godfather- Frank Sinatra
Sam Fableman from the Fablemans- Steven Spielberg
Lancaster Dodd from The Master- L. Ron Hubbard