How do you kill certain drugs?

I'm starting an art piece. I'm looking to put together a bunch of drugs.

Now I have blotter tab of lsd which is old and has been in the sunlight so it's definitely dead. But I also have ketamine, Molly, and a shard of cocaine. Is there a way to make these substances dead? Ie. incapable of getting someone high.

Edit: to those of you saying, "asking for ideas makes it not your art", are you daft? Do you understand what are is? Is Van Goghs starry night not his art because he used the sky as an influence? Did Edison not invent the long-lasting light bulb, even though he stole the idea from Tesla?