new research shows PGT-a testing is only 40% accurate
Hi, I know this board is very pro-testing but newest research shows how inaccurate PGT-a testing is. The second journal article I posted from Russia tested the trophectoderm used in PGT-a and then the inner morula of discarded blasts and found only 40% correlation. In fact, 90% of the time, PGT-a tested aneuoploids are either euoploids or mosaics. This article was just published a few months ago. Complex mosaics can self correct. Top American scientists have been saying this for years - that the embryo self corrects and pushes the aneuploid cells to the trophectoderm.
The first journal article is from a famous American RE, and he drew a picture that shows why PGT-a testing is highly inaccurate.
I know this board is very pro PGT-a but: at the end of the day your clinic is about making profit. People fail euploid transfers all the time, get miscarriages from a PGT-a tested embryo and untested embryos do fine all the time - just search Reddit for anecdotal evidence. People say, "I tested and I saved myself so many miscarriages" - yes but how do you know for sure unless you tried these embryos out in your body? If you have a lot of embryos fine but if you have DOR or are older, you don't you could be discarding perfectly good blasts.
First article:
https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(20)30313-030313-0)
Edited to add: 2nd journal article - didn't post properly in the OP: