Experience with Methylene blue.
So I've been taking Methylene blue (usp grade of course) for a couple months now.
Ive always suffered from chronic fatigue, microsleep, brain fog, bad blood circulation. Amongst others.
I started with a dose of like 5 to 8mg daily. It improved my brain fog within a few days, and for the first time in my life I had warm hands (improved circulation happens like an hour after ingestion. Small amounts of MB act as a vasodilator.)
After a while of taking that dose, i noticed that colour's appeared more distinct and brighter. After another few days that brightness caused eye sensitivity and chronic headaches.
I assume it's the work of MBs MAOI effects, since it felt almost identical to how sertraline made me feel. I stopped for a while. Sensitivity to light disappeared, headache was gone, but brainfog was starting to creep back in.
I then started again, this time at much lower doses, since MBs effect on mitochondrial function are my main goal, and those were observed at doses as small as 500micrograms. So I take 2 drops, roughly one milligram, one time daily. Been doing that for like 2 months now.
My energy levels are stable, I can finally watch a movie without falling asleep. Feels like my brain, after being cluttered and full of cottons is now an open field with thoughts racing through. The speed of my mental calculations has risen drastically, and my inability to visualize thoughts has improved. Before, I thought I had afantasia. Now it works fine, unless my mind Is racing from stress.
Other than that I've seen slight improvement in the health of my skin, but that's negligible.
Now, I can't credit everything to MB as I've done other life changes, but I do notice a lot of my issues seem to follow along when I stop or start MB with a delay of a few days.