What are my options for frown lines?

45 years old, I’ve started Tret (0.025%) and Estrogen Boost from Musely. Is there anything non-surgical that will help get these frown lines out? Is Filler the best option? It scares me a lot…. But let me know your stories!

I am not interested in a face lift so the jowls will just be what they are unless anyone has non-surgical options!